David F. Cauble, Ph.D.

David F. Cauble, Ph.D.

Technical Specialist

Tel. 617.994.0798
Fax 617.742.4214
Email: dcauble@lahive.com

Background

Education

  • North Carolina State University, B.S., Chemistry, 1996
  • University of Texas at Austin, Ph.D., Organic Chemistry, 2004

Professional Involvement

  • American Chemical Society

Honors & Awards

  • Welch Summer Research Fellowship 2003
  • Welch Professional Development Award, The University of Texas at Austin, 2002
  • Welch Teaching Excellence Award, 2000

Practice Areas

Life Sciences, Patents

Industry & Technical Focus

Biotechnology, Chemistry, Pharmaceuticals

Practice Description

Dr. Cauble is an experienced chemist with pharmaceutical industry experience and academic research experience. He assists clients with patent preparation and prosecution. As a Senior Scientist at Schering-Plough Research Institute, David’s studies involved exploration of biological pathways implicated in cancer through the discovery and application of small molecule protein kinase inhibitors. David is also an inventor and co-author on 6 US patents that detail the application of liquid carbon dioxide-based technologies within the textile industry.

Notable Experience

  • Assisting with the preparation and prosecution of U.S. and foreign patent applications in the fields of small molecules, biologics, synthetic methods, drug delivery compositions, polymers, materials science, and medical devices.
  • Conducting freedom to operate analyses and drafting infringement and invalidity opinions.
  • Conducted postdoctoral work at Stanford University, in the labs of Professor Barry Trost. David’s work focused on advancing the syntheses of the marine macrolide (-)-dactylolide and the diterpenoid glycoside cotylenin A.
  • Extensive research in the development of novel synthetic methods, including an enantioselective, organocatalytic photocycloaddition and the discovery of a catalytic, anion radical-mediated [2+2] cycloaddition.
     

Prior Experience

  • Senior Scientist, Medicinal Chemistry at Schering-Plough Research Institute. Designed and synthesized novel kinase inhibitors for multiple targets within oncology program. Drafted and reviewed internal proposals for novel ligand libraries.
  • Postdoctoral Associate at Stanford University in Professor Barry Trost’s labs.
  • Graduate Research Assistant at the University of Texas at Austin in Professor Michael Krische’s labs.
  • Chemist at Micell Technologies. Created proprietary detergent products involving liquid carbon dioxide-based technologies.
     

Publications & Speaking Engagements

  • Contributor to 6 peer-reviewed research articles published in the Journal of American Chemical Society, and the Journal of Organic Chemistry.
  • Poster Presentation, William S. Johnson Symposium, Stanford University, 2006.
  • Poster Presentation, ACS National Meeting, Orlando, 2002.
     

Case studies

 
 
Our Thinking Expands Yours

The client, a midsized pharmaceutical company, wanted an in-license to work with a compound that has potential therapeutic applications for treatment of hepatitis C. » read more

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